Functional correction of adult mdx mouse muscle using gutted adenoviral vectors expressing full-length dystrophin
Duchenne muscular dystrophy is a lethal X-linked recessive disorder caused by mutations in the dystrophin gene. Delivery of functionally effective levels of dystrophin to immunocompetent, adult mdx (dystrophin-deficient) mice has been challenging because of the size of the gene, immune responses aga...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC130572/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12271128/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.202300099 |
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