p38 MAPK enhances STAT1-dependent transcription independently of Ser-727 phosphorylation

The transcription factor signal transducer and activator of transcription 1 (STAT1) requires phosphorylation at both Tyr-701 and Ser-727 for full activation. IFN-γ induces phosphorylation of both residues, whereas stress signals like UV or lipopolysaccharide stimulate phosphorylation of Ser-727 only...

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Bibliografiska uppgifter
Huvudupphovsmän: Ramsauer, Katrin, Sadzak, Iwona, Porras, Almudena, Pilz, Andreas, Nebreda, Angel R., Decker, Thomas, Kovarik, Pavel
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2002
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC130550/
https://ncbi.nlm.nih.gov/pubmed/12232043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192264999
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