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Untangling the wires: A strategy to trace functional interactions in signaling and gene networks

Emerging technologies have enabled the acquisition of large genomics and proteomics data sets. However, current methodologies for analysis do not permit interpretation of the data in ways that unravel cellular networking. We propose a quantitative method for determining functional interactions in ce...

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Detalhes bibliográficos
Main Authors: Kholodenko, Boris N., Kiyatkin, Anatoly, Bruggeman, Frank J., Sontag, Eduardo, Westerhoff, Hans V., Hoek, Jan B.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC130547/
https://ncbi.nlm.nih.gov/pubmed/12242336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192442699
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