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Molecular Dynamics Simulations Indicate a Possible Role of Parallel β-Helices in Seeded Aggregation of Poly-Gln

The molecular structures of amyloid fibers characterizing neurodegenerative diseases such as Huntington's or transmissible spongiform encephalopathies are unknown. Recently, x-ray diffraction patterns of poly-Gln fibers and electron microscopy images of two-dimensional crystals formed from buil...

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Detalhes bibliográficos
Main Authors: Stork, Martina, Giese, Armin, Kretzschmar, Hans A., Tavan, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305343/
https://ncbi.nlm.nih.gov/pubmed/15665127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.052415
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