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Polymorphism of Pyridinium Amphiphiles for Gene Delivery: Influence of Ionic Strength, Helper Lipid Content, and Plasmid DNA Complexation

Two double-tailed pyridinium cationic amphiphiles, differing only in the degree of unsaturation of the alkyl chains, have been selected for a detailed study of their aggregation behavior, under conditions employed for transfection experiments. The transfection efficiencies of the two molecules are r...

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Detalhes bibliográficos
Main Authors: Scarzello, Marco, Chupin, Vladimir, Wagenaar, Anno, Stuart, Marc C. A., Engberts, Jan B. F. N., Hulst, Ron
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305262/
https://ncbi.nlm.nih.gov/pubmed/15613636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.053983
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