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Contribution of Hydrophobicity to Thermodynamics of Ligand-DNA Binding and DNA Collapse

The importance of understanding the dynamics of DNA condensation is inherent in the biological significance of DNA packaging in cell nuclei, as well as for gene therapy applications. Specifically, the role of ligand hydrophobicity in DNA condensation has received little attention. Considering that o...

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Bibliografiske detaljer
Main Authors: Patel, Mayank M., Anchordoquy, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305261/
https://ncbi.nlm.nih.gov/pubmed/15653734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.052100
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