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Tetrameric Mouse Acetylcholinesterase: Continuum Diffusion Rate Calculations by Solving the Steady-State Smoluchowski Equation Using Finite Element Methods

The tetramer is the most important form for acetylcholinesterase in physiological conditions, i.e., in the neuromuscular junction and the nervous system. It is important to study the diffusion of acetylcholine to the active sites of the tetrameric enzyme to understand the overall signal transduction...

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Hlavní autoři: Zhang, Deqiang, Suen, Jason, Zhang, Yongjie, Song, Yuhua, Radic, Zoran, Taylor, Palmer, Holst, Michael J., Bajaj, Chandrajit, Baker, Nathan A., McCammon, J. Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305222/
https://ncbi.nlm.nih.gov/pubmed/15626705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.053850
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