Tetrameric Mouse Acetylcholinesterase: Continuum Diffusion Rate Calculations by Solving the Steady-State Smoluchowski Equation Using Finite Element Methods

The tetramer is the most important form for acetylcholinesterase in physiological conditions, i.e., in the neuromuscular junction and the nervous system. It is important to study the diffusion of acetylcholine to the active sites of the tetrameric enzyme to understand the overall signal transduction...

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Detalhes bibliográficos
Main Authors: Zhang, Deqiang, Suen, Jason, Zhang, Yongjie, Song, Yuhua, Radic, Zoran, Taylor, Palmer, Holst, Michael J., Bajaj, Chandrajit, Baker, Nathan A., McCammon, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Biophysical Theory and Modeling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305222/
https://ncbi.nlm.nih.gov/pubmed/15626705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.053850
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