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A Model for the Mediation of Processivity of DNA-Targeting Proteins by Nonspecific Binding: Dependence on DNA Length and Presence of Obstacles
A physical and mathematical model is presented to explain processivity of proteins on DNA. In this model, a DNA-targeting protein such as a restriction enzyme can diffuse to the DNA surface and nonspecifically bind to it. Once on the DNA surface it will either move along the DNA or equilibrate with...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Biophysical Society
2005
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1305217/ https://ncbi.nlm.nih.gov/pubmed/15596498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.052688 |
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