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Structural characterization of the PIT-1/ETS-1 interaction: PIT-1 phosphorylation regulates PIT-1/ETS-1 binding

The POU-domain transcription factor Pit-1 and Ets-1, a member of the ETS family of transcription factors, can associate in solution and synergistically activate the prolactin promoter by binding to a composite response element in the prolactin promoter. We mapped the minimal region of Ets-1 required...

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Autors principals: Augustijn, Kevin D., Duval, Dawn L., Wechselberger, Rainer, Kaptein, Rob, Gutierrez-Hartmann, Arthur, van der Vliet, Peter C.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC130516/
https://ncbi.nlm.nih.gov/pubmed/12242337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192693499
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