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Molecular Dynamics Simulations of Discoidal Bilayers Assembled from Truncated Human Lipoproteins

Human apolipoprotein A-1 (apo A-1) is the major protein component of high-density lipoproteins. The apo A-1 lipid-binding domain was used as a template for the synthesis of amphipathic helical proteins termed membrane scaffold proteins, employed to self-assemble soluble monodisperse discoidal partic...

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Detalhes bibliográficos
Main Authors: Shih, Amy Y., Denisov, Ilia G., Phillips, James C., Sligar, Stephen G., Schulten, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305032/
https://ncbi.nlm.nih.gov/pubmed/15533924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.046896
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