Structural Variation in Human Apolipoprotein E3 and E4: Secondary Structure, Tertiary Structure, and Size Distribution

Human apolipoprotein E (apoE) is a 299-amino-acid protein with a molecular weight of 34 kDa. The difference between the apoE3 and apoE4 isoforms is a single residue substitution involving a Cys-Arg replacement at residue 112. ApoE4 is positively associated with atherosclerosis and late-onset and spo...

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Bibliografiska uppgifter
Huvudupphovsmän: Chou, Chi-Yuan, Lin, Yi-Ling, Huang, Yu-Chyi, Sheu, Sheh-Yi, Lin, Ta-Hsien, Tsay, Huey-Jen, Chang, Gu-Gang, Shiao, Ming-Shi
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2005
Ämnen:
Proteins
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305022/
https://ncbi.nlm.nih.gov/pubmed/15475580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.046813
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