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Aggregation of Normal and Sickle Hemoglobin in High Concentration Phosphate Buffer

Sickle cell disease is caused by a mutant form of hemoglobin, hemoglobin S, that polymerizes under hypoxic conditions. The extent and mechanism of polymerization are thus the subject of many studies of the pathophysiology of the disease and potential treatment strategies. To facilitate such studies,...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Kejing, Ballas, Samir K., Hantgan, Roy R., Kim-Shapiro, Daniel B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Biophysical Society 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304920/
https://ncbi.nlm.nih.gov/pubmed/15465861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.046482
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