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Rearrangement of the 16S Precursor Subunits Is Essential for the Formation of the Active 20S Proteasome

Proteasome-dependent proteolysis is essential for a number of key cellular processes and requires a sophisticated biogenesis pathway to function. Here, we have arrested the assembly process in its dynamic progression at the short-lived 16S state. Structural analysis of the 16S proteasome precursor i...

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Bibliografische gegevens
Hoofdauteurs: Mullapudi, Srinivas, Pullan, Lee, Bishop, Ozlem T., Khalil, Hassan, Stoops, James K., Beckmann, Roland, Kloetzel, Peter M., Krüger, Elke, Penczek, Pawel A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Biophysical Society 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304918/
https://ncbi.nlm.nih.gov/pubmed/15361411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051144
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