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Effects of Two Familial Hypertrophic Cardiomyopathy Mutations in α-Tropomyosin, Asp175Asn and Glu180Gly, on the Thermal Unfolding of Actin-Bound Tropomyosin

Differential scanning calorimetry was used to investigate the thermal unfolding of native α-tropomyosin (Tm), wild-type α-Tm expressed in Escherichia coli and the wild-type α-Tm carrying either of two missense mutations associated with familial hypertrophic cardiomyopathy, D175N or E180G. Recombinan...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Kremneva, Elena, Boussouf, Sabrina, Nikolaeva, Olga, Maytum, Robin, Geeves, Michael A., Levitsky, Dmitrii I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Biophysical Society 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304903/
https://ncbi.nlm.nih.gov/pubmed/15454401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.048793
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