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Equilibrium Structure and Folding of a Helix-Forming Peptide: Circular Dichroism Measurements and Replica-Exchange Molecular Dynamics Simulations

We have performed experimental measurements and computer simulations of the equilibrium structure and folding of a 21-residue α-helical heteropeptide. Far ultraviolet circular dichroism spectroscopy is used to identify the presence of helical structure and to measure the thermal unfolding curve. The...

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Autori principali: Jas, Gouri S., Kuczera, Krzysztof
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304891/
https://ncbi.nlm.nih.gov/pubmed/15339816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.045419
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