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Pressure Denaturation of Staphylococcal Nuclease Studied by Neutron Small-Angle Scattering and Molecular Simulation
We studied the pressure-induced folding/unfolding transition of staphylococcal nuclease (SN) over a pressure range of ∼1–3 kilobars at 25°C by small-angle neutron scattering and molecular dynamics simulations. We find that applying pressure leads to a twofold increase in the radius of gyration deriv...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Biophysical Society
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304814/ https://ncbi.nlm.nih.gov/pubmed/15347583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.050526 |
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