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Analysis of Side-Chain Rotamers in Transmembrane Proteins

We measured the frequency of side-chain rotamers in 14 α-helical and 16 β-barrel membrane protein structures and found that the membrane environment considerably perturbs the rotamer frequencies compared to soluble proteins. Although there are limited experimental data, we found statistically signif...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chamberlain, Aaron K., Bowie, James U.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304812/
https://ncbi.nlm.nih.gov/pubmed/15339811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.044024
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