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Rotamer libraries and probabilities of transition between rotamers for the side chains in protein-protein binding

Conformational changes in the side chains are essential for protein-protein binding. Rotameric states and unbound-to-bound conformational changes in the surface residues were systematically studied on a representative set of protein complexes. The side-chain conformations were mapped onto dihedral a...

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Detalhes bibliográficos
Main Authors: Kirys, Tatsiana, Ruvinsky, Anatoly M., Tuzikov, Alexander V., Vakser, Ilya A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393779/
https://ncbi.nlm.nih.gov/pubmed/22544766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24103
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