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Dynamics of the DNA Duplex Formation Studied by Single Molecule Force Measurements

DNA is partly denatured in vitro by applying a force that mechanically separates the two strands of the double helix. Sudden reduction of the imposed displacement triggers spontaneous reannealing of the molecule. The corresponding force signals are measured by optical trapping interferometry for bac...

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Detalles Bibliográficos
Main Authors: Bockelmann, U., Thomen, P., Heslot, F.
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304805/
https://ncbi.nlm.nih.gov/pubmed/15339815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.039776
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