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Dynamics of the DNA Duplex Formation Studied by Single Molecule Force Measurements

DNA is partly denatured in vitro by applying a force that mechanically separates the two strands of the double helix. Sudden reduction of the imposed displacement triggers spontaneous reannealing of the molecule. The corresponding force signals are measured by optical trapping interferometry for bac...

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Hlavní autoři: Bockelmann, U., Thomen, P., Heslot, F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304805/
https://ncbi.nlm.nih.gov/pubmed/15339815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.039776
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