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Stability of the Heme Environment of the Nitric Oxide Synthase from Staphylococcus aureus in the Absence of Pterin Cofactor

We have used resonance Raman spectroscopy to probe the heme environment of a recently discovered NOS from the pathogenic bacterium Staphylococcus aureus, named SANOS. We detect two forms of the CO complex in the absence of L-arginine, with ν(Fe-CO) at 482 and 497 cm(−1) and ν(C-O) at 1949 and 1930 c...

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Detalhes bibliográficos
Main Authors: Chartier, François J. M., Couture, Manon
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304597/
https://ncbi.nlm.nih.gov/pubmed/15345570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.042119
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