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The Two Motor Domains of KIF3A/B Coordinate for Processive Motility and Move at Different Speeds

KIF3A/B, a kinesin involved in intraflagellar transport and Golgi trafficking, is distinctive because it contains two nonidentical motor domains. Our hypothesis is that the two heads have distinct functional properties, which are tuned to maximize the performance of the wild-type heterodimer. To tes...

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Detalhes bibliográficos
Main Authors: Zhang, Yangrong, Hancock, William O.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304584/
https://ncbi.nlm.nih.gov/pubmed/15345558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.039842
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