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Rational Design of Solution Additives for the Prevention of Protein Aggregation

We have developed a statistical-mechanical model of the effect of solution additives on protein association reactions. This model incorporates solvent radial distribution functions obtained from all-atom molecular dynamics simulations of particular proteins into simple models of protein interactions...

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Detalhes bibliográficos
Main Authors: Baynes, Brian M., Trout, Bernhardt L.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304568/
https://ncbi.nlm.nih.gov/pubmed/15345542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.042473
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