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Conformational Changes of the Ca(2+) Regulatory Site of the Na(+)-Ca(2+) Exchanger Detected by FRET
The Na(+)-Ca(2+) exchanger is a plasma membrane protein expressed at high levels in cardiomyocytes. It extrudes 1 Ca(2+) for 3 Na(+) ions entering the cell, regulating intracellular Ca(2+) levels and thereby contractility. Na(+)-Ca(2+) exchanger activity is regulated by intracellular Ca(2+), which b...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Biophysical Society
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304498/ https://ncbi.nlm.nih.gov/pubmed/15298897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.043471 |
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