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Hill Coefficient for Estimating the Magnitude of Cooperativity in Gating Transitions of Voltage-Dependent Ion Channels

A frequently used measure for the extent of cooperativity in ligand binding by an allosteric protein is the Hill coefficient, obtained by fitting data of initial reaction velocity (or fractional binding saturation) as a function of substrate concentration to the Hill equation. Here, it is demonstrat...

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Détails bibliographiques
Auteur principal: Yifrach, Ofer
Format: Artigo
Langue:Inglês
Publié: Biophysical Society 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304492/
https://ncbi.nlm.nih.gov/pubmed/15298891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.040410
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