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Hill Coefficient for Estimating the Magnitude of Cooperativity in Gating Transitions of Voltage-Dependent Ion Channels

A frequently used measure for the extent of cooperativity in ligand binding by an allosteric protein is the Hill coefficient, obtained by fitting data of initial reaction velocity (or fractional binding saturation) as a function of substrate concentration to the Hill equation. Here, it is demonstrat...

Täydet tiedot

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Bibliografiset tiedot
Päätekijä: Yifrach, Ofer
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Biophysical Society 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304492/
https://ncbi.nlm.nih.gov/pubmed/15298891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.040410
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