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Hill Coefficient for Estimating the Magnitude of Cooperativity in Gating Transitions of Voltage-Dependent Ion Channels

A frequently used measure for the extent of cooperativity in ligand binding by an allosteric protein is the Hill coefficient, obtained by fitting data of initial reaction velocity (or fractional binding saturation) as a function of substrate concentration to the Hill equation. Here, it is demonstrat...

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Bibliografiske detaljer
Hovedforfatter: Yifrach, Ofer
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304492/
https://ncbi.nlm.nih.gov/pubmed/15298891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.040410
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