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Exploring the Counterion Atmosphere around DNA: What Can Be Learned from Molecular Dynamics Simulations?

The counterion distribution around a DNA dodecamer (5′-CGCGAATTCGCG-3′) is analyzed using both standard and novel techniques based on state of the art molecular dynamics simulations. Specifically, we have explored the population of Na(+) in the minor groove of DNA duplex, and whether or not a string...

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Detalhes bibliográficos
Main Authors: Rueda, Manuel, Cubero, Elena, Laughton, Charles A., Orozco, Modesto
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304490/
https://ncbi.nlm.nih.gov/pubmed/15298889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.040451
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