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Free Diffusion of Steroid Hormones Across Biomembranes: A Simplex Search with Implicit Solvent Model Calculations

Steroid hormones such as progesterone, testosterone, and estradiol are derived from cholesterol, a major constituent of biomembranes. Although the hormones might be expected to associate with the bilayer in a fashion similar to that of cholesterol, their biological action in regulating transcription...

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Detalhes bibliográficos
Main Authors: Oren, Idit, Fleishman, Sarel J., Kessel, Amit, Ben-Tal, Nir
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304487/
https://ncbi.nlm.nih.gov/pubmed/15298886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.035527
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