Continuum solvent model calculations of alamethicin-membrane interactions: thermodynamic aspects.

Alamethicin is a 20-amino acid antibiotic peptide that forms voltage-gated ion channels in lipid bilayers. Here we report calculations of its association free energy with membranes. The calculations take into account the various free-energy terms that contribute to the transfer of the peptide from t...

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Hlavní autoři: Kessel, A, Cafiso, D S, Ben-Tal, N
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300662/
https://ncbi.nlm.nih.gov/pubmed/10653772
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