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Microscopic Mechanism of Antibiotics Translocation through a Porin

OmpF from the outer membrane of Escherichia coli is a general porin considered to be the main pathway for β-lactam antibiotics. The availability of a high-resolution crystal structure of OmpF and new experimental techniques at the single-molecule level have opened the way to the investigation of the...

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Bibliografske podrobnosti
Main Authors: Ceccarelli, Matteo, Danelon, Christophe, Laio, Alessandro, Parrinello, Michele
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304379/
https://ncbi.nlm.nih.gov/pubmed/15240444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.037283
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