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Freely Diffusing Single Hairpin Ribozymes Provide Insights into the Role of Secondary Structure and Partially Folded States in RNA Folding

Single-molecule fluorescence resonance energy transfer studies of freely diffusing hairpin ribozymes with different combinations of helical junction and loop elements reveal striking differences in their folding behavior. We examined a series of six different ribozymes consisting of two-, three- and...

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Detalhes bibliográficos
Main Authors: Pljevaljčić, Goran, Millar, David P., Deniz, Ashok A.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304366/
https://ncbi.nlm.nih.gov/pubmed/15240479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.036087
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