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Modeling Noncompetitive Antagonism of a Nicotinic Acetylcholine Receptor
Models of closed and open channel pores of a muscle-type nicotinic acetylcholine receptor (nAChR) channel comprising M1 and M2 segments are presented. A model of the closed channel is proposed in which hydrophobic residues of the Equatorial Leucine ring screen the oxygen domain formed by the Serine...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Biophysical Society
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304339/ https://ncbi.nlm.nih.gov/pubmed/15240454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.037457 |
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