The Stability and Dynamics of the Human Calcitonin Amyloid Peptide DFNKF

The stability and dynamics of the human calcitonin-derived peptide DFNKF (hCT(15–19)) are studied using molecular dynamics (MD) simulations. Experimentally, this peptide is highly amyloidogenic and forms fibrils similar to the full length calcitonin. Previous comparative MD studies have found that t...

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Hlavní autoři: Tsai, Hui-Hsu (Gavin), Zanuy, David, Haspel, Nurit, Gunasekaran, Kannan, Ma, Buyong, Tsai, Chung-Jung, Nussinov, Ruth
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2004
Témata:
Biophysical Theory and Modeling
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304338/
https://ncbi.nlm.nih.gov/pubmed/15240453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.040352
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