Načítá se...

Computer Simulation of Small Molecule Permeation across a Lipid Bilayer: Dependence on Bilayer Properties and Solute Volume, Size, and Cross-Sectional Area

Cell membrane permeation is required for most drugs to reach their biological target, and understanding this process is therefore crucial for rational drug design. Recent molecular dynamics simulations have studied the permeation of eight small molecules through a phospholipid bilayer. Unlike experi...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bemporad, D., Luttmann, C., Essex, J. W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304332/
https://ncbi.nlm.nih.gov/pubmed/15240439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.030601
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!