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Fast Dynamics and Stabilization of Proteins: Binary Glasses of Trehalose and Glycerol

We present elastic and inelastic incoherent neutron scattering data from a series of trehalose glasses diluted with glycerol. A strong correlation with recently published protein stability data in the same series of glasses illustrates that the dynamics at Q ≥ 0.71 Å(−1) and ω > 200 MHz are impor...

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Detalles Bibliográficos
Main Authors: Cicerone, Marcus T., Soles, Christopher L.
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304285/
https://ncbi.nlm.nih.gov/pubmed/15189880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.035519
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