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Cysteine Scanning of MscL Transmembrane Domains Reveals Residues Critical for Mechanosensitive Channel Gating

The mechanosensitive channel of large conductance (MscL), a bacterial channel, is perhaps the best characterized mechanosensitive protein. A structure of the Mycobacterium tuberculosis ortholog has been solved by x-ray crystallography, but details of how the channel gates remain obscure. Here, cyste...

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Autores principales: Levin, Gal, Blount, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: Biophysical Society 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304155/
https://ncbi.nlm.nih.gov/pubmed/15111403
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