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Nanometer Analysis of Cell Spreading on Matrix-Coated Surfaces Reveals Two Distinct Cell States and STEPs

When mouse embryonic fibroblasts in suspension contact a matrix-coated surface, they rapidly adhere and spread. Using total internal reflection fluorescence microscopy of dye-loaded fibroblasts to quantify cell-substrate contact, we found that increasing the surface matrix density resulted in faster...

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Detalhes bibliográficos
Main Authors: Dubin-Thaler, Benjamin J., Giannone, Gregory, Döbereiner, Hans-Günther, Sheetz, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304013/
https://ncbi.nlm.nih.gov/pubmed/14990505
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