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Crystal Structure of the Hyperthermophilic Inorganic Pyrophosphatase from the Archaeon Pyrococcus horikoshii

A homolog to the eubacteria inorganic pyrophosphatase (PPase, EC 3.6.1.1) was found in the genome of the hyperthermophilic archaeon Pyrococcus horikoshii. This inorganic pyrophosphatase (Pho-PPase) grows optimally at 88°C. To understand the structural basis for the thermostability of Pho-PPase, we h...

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Bibliographic Details
Main Authors: Liu, Binbin, Bartlam, Mark, Gao, Renjun, Zhou, Weihong, Pang, Hai, Liu, Yiwei, Feng, Yan, Rao, Zihe
Format: Artigo
Language:Inglês
Published: Biophysical Society 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303807/
https://ncbi.nlm.nih.gov/pubmed/14695284
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