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Oligomerization of Fusogenic Peptides Promotes Membrane Fusion by Enhancing Membrane Destabilization

A key element of membrane fusion reactions in biology is the involvement of specific fusion proteins. In many viruses, the proteins that mediate membrane fusion usually exist as homotrimers. Furthermore, they contain extended triple-helical coiled-coil domains and fusogenic peptides. It has been sug...

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Detalhes bibliográficos
Main Authors: Lau, Wai Leung, Ege, David S., Lear, James D., Hammer, Daniel A., DeGrado, William F.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303790/
https://ncbi.nlm.nih.gov/pubmed/14695269
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