In Situ Detection of Mycobacterium tuberculosis Transcripts in Human Lung Granulomas Reveals Differential Gene Expression in Necrotic Lesions

We have used RNA-RNA in situ hybridization to detect the expression of several Mycobacterium tuberculosis genes in tuberculous granulomas in lung tissue sections from tuberculosis patients. The M. tuberculosis genes chosen fall into two classes. Four genes (icl, narX, and Rv2557 and Rv2558) have bee...

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Pubblicato in:	Infect Immun
Autori principali:	Fenhalls, Gael, Stevens, Liesel, Moses, Lorraine, Bezuidenhout, Juanita, Betts, Joanna C., Helden, Paul van, Lukey, Pauline T., Duncan, Ken
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Molecular Pathogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC130373/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12379712/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.11.6330-6338.2002
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