In Situ Detection of Mycobacterium tuberculosis Transcripts in Human Lung Granulomas Reveals Differential Gene Expression in Necrotic Lesions

We have used RNA-RNA in situ hybridization to detect the expression of several Mycobacterium tuberculosis genes in tuberculous granulomas in lung tissue sections from tuberculosis patients. The M. tuberculosis genes chosen fall into two classes. Four genes (icl, narX, and Rv2557 and Rv2558) have bee...

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Detalhes bibliográficos
Main Authors: Fenhalls, Gael, Stevens, Liesel, Moses, Lorraine, Bezuidenhout, Juanita, Betts, Joanna C., Helden, Paul van, Lukey, Pauline T., Duncan, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC130373/
https://ncbi.nlm.nih.gov/pubmed/12379712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.11.6330-6338.2002
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