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Avidity Modulation Activates Adhesion under Flow and Requires Cooperativity among Adhesion Receptors

An early step in activation of leukocyte adhesion is a release of integrins from cytoskeletal constraints on their diffusion, leading to rearrangement and, consequently, increased avidity. Static adhesion assays using purified ligand as a substrate have demonstrated that very low doses of cytochalas...

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Detalhes bibliográficos
Main Authors: Ni, Na, Kevil, Christopher G., Bullard, Daniel C., Kucik, Dennis F.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303711/
https://ncbi.nlm.nih.gov/pubmed/14645099
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