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Probing Conformational Changes of Gramicidin Ion Channels by Single-Molecule Patch-Clamp Fluorescence Microscopy

Complex conformational changes influence and regulate the dynamics of ion channels. Such conformational changes are stochastic and often inhomogeneous, which makes it extremely difficult, if not impossible, to characterize them by ensemble-averaged experiments or by single-channel recordings of the...

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Detalhes bibliográficos
Main Authors: Harms, Greg S., Orr, Galya, Montal, Mauricio, Thrall, Brian D., Colson, Steve D., Lu, H. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303355/
https://ncbi.nlm.nih.gov/pubmed/12944296
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