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Structural Insights into the Effect of Hydration and Ions on A-Tract DNA: A Molecular Dynamics Study

DNA structure is known to be sensitive to hydration and ionic environment. To explore the dynamics, hydration, and ion binding features of A-tract sequences, a 7-ns Molecular dynamics (MD) study has been performed on the dodecamer d(CGCAAATTTGCG)(2). The results suggest that the intrusion of Na(+) i...

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Detalhes bibliográficos
Main Authors: Madhumalar, A., Bansal, Manju
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303353/
https://ncbi.nlm.nih.gov/pubmed/12944294
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