A Molecular View of the Dynamics of dsDNA Packing Inside Viral Capsids in the Presence of Ions

Genome packing in viruses and prokaryotes relies on positively charged ions to reduce electrostatic repulsions, and induce attractions that can facilitate DNA condensation. Here we present molecular dynamics simulations spanning several microseconds of dsDNA packing inside nanometer-sized viral caps...

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Bibliographic Details
Published in:Biophys J
Main Authors: Córdoba, Andrés, Hinckley, Daniel M., Lequieu, Joshua, de Pablo, Juan J.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2017
Subjects:
Nucleic Acids and Genome Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389966/
https://ncbi.nlm.nih.gov/pubmed/28402874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.02.015
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