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Two-State Folding over a Weak Free-Energy Barrier

We present a Monte Carlo study of a model protein with 54 amino acids that folds directly to its native three-helix-bundle state without forming any well-defined intermediate state. The free-energy barrier separating the native and unfolded states of this protein is found to be weak, even at the fol...

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Bibliografski detalji
Glavni autori: Favrin, Giorgio, Irbäck, Anders, Samuelsson, Björn, Wallin, Stefan
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303322/
https://ncbi.nlm.nih.gov/pubmed/12944263
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