A Comparison of Murine and Human Immunoproteomes of Helicobacter pylori Validates the Preclinical Murine Infection Model for Antigen Screening

Preclinical mouse infection models are widely used for Helicobacter vaccine development, but how well such models mimic important aspects of human infections is unknown. A comparison of Helicobacter pylori immunoproteomes of infected mice with previously reported patient data reveals a high agreemen...

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Bibliographische Detailangaben
Hauptverfasser: Bumann, Dirk, Holland, Petra, Siejak, Frank, Koesling, Jan, Sabarth, Nicolas, Lamer, Stefanie, Zimny-Arndt, Ursula, Jungblut, Peter R., Meyer, Thomas F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Molecular Genomics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC130298/
https://ncbi.nlm.nih.gov/pubmed/12379736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.11.6494-6498.2002
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