A Comparison of Murine and Human Immunoproteomes of Helicobacter pylori Validates the Preclinical Murine Infection Model for Antigen Screening

Preclinical mouse infection models are widely used for Helicobacter vaccine development, but how well such models mimic important aspects of human infections is unknown. A comparison of Helicobacter pylori immunoproteomes of infected mice with previously reported patient data reveals a high agreemen...

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Detalhes bibliográficos
Main Authors: Bumann, Dirk, Holland, Petra, Siejak, Frank, Koesling, Jan, Sabarth, Nicolas, Lamer, Stefanie, Zimny-Arndt, Ursula, Jungblut, Peter R., Meyer, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Molecular Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC130298/
https://ncbi.nlm.nih.gov/pubmed/12379736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.11.6494-6498.2002
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