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A Physical Model of Potassium Channel Activation: From Energy Landscape to Gating Kinetics

We have developed a method for rapidly computing gating currents from a multiparticle ion channel model. Our approach is appropriate for energy landscapes that can be characterized by a network of well-defined activation pathways with barriers. To illustrate, we represented the gating apparatus of a...

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Hlavní autoři: Sigg, Daniel, Bezanilla, Francisco
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302953/
https://ncbi.nlm.nih.gov/pubmed/12770877
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