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Two Components of Voltage-Dependent Inactivation in Ca(v)1.2 Channels Revealed by Its Gating Currents

Voltage-dependent inactivation (VDI) was studied through its effects on the voltage sensor in Ca(v)1.2 channels expressed in tsA 201 cells. Two kinetically distinct phases of VDI in onset and recovery suggest the presence of dual VDI processes. Upon increasing duration of conditioning depolarization...

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Bibliografske podrobnosti
Main Authors: Ferreira, Gonzalo, Ríos, Eduardo, Reyes, Nicolás
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302950/
https://ncbi.nlm.nih.gov/pubmed/12770874
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